Abstract

Author:
Nur Ain Mohamad Nasri, Juliana Jumal

Doi: 10.26480/jwbm.01.2020.09.14

This is an open access article distributed under the Creative Commons Attribution License CC BY 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Two benzoyl phenylthiourea derivatives namely: 1-benzoyl-3-(4-bromophenyl)-2- thiourea (M) and 1-(4-chlorobenzoyl)-3-(4-methylphenyl)-2-thiourea (MI) were successfully synthesized and characterized by using Carbon, Hydrogen and Nitrogen (CHN) micro elemental analysis, Fourier Transform Infra-Red (FTIR) and Nuclear Magnetic Resonance (NMR) spectroscopy methods. Elemental analysis for M (C14H11N2SOBr) and MI (C15H13N2SOCl) were compatible with the expected theoretical calculation. The FTIR spectrum obtained for M and MI compounds show the presence of four important functional groups; ʋ(N-H), ʋ(C=O), ʋ(C-N) and ʋ(C=S) that appeared at 3380-3367 cm-1, 1666-1681 cm-1, 1342-1268 cm-1 and 1146-1152 cm-1, respectively. The NMR spectrum data for MI shows the chemical shift at 6.63-7.85 ppm for Ar-H group, 2.26-2.40 ppm for methyl group, 7.44 ppm for N1H and 3.09 ppm for N2H. For the application, M and MI were used as probes in detecting Cd2+ in methanol solution. UV-Visible spectrophotometer was used to analyze the absorbance values of the compound before and after Cd2+ was added. It is found that compound M displayed the behavior of ‘turn off’ sensors while compound MI possessed the behavior of ‘turn on’ when detecting 0.5×10-5 M and 1×10- 5 M of Cd2+ ion. The behavior of ‘turn on’ and ‘turn off’ is due to the increasing or decreasing of absorbance when Cd2+ was added to the compounds.